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  • Biological Production Section
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Biological Production Section

Responsibilities:-

a).General: Deals with bacterial vaccine production, i.e. Anthrax, haemorrhagic septicaemia and blackleg. Production of antisera for various bacteria. Standardization of vaccines.  This includes safety, potency and efficacy testing.  Preparation of the seed for the vaccine and checking of purity. Investigation on bacterial diseases and outbreaks.  Research to improve quality of vaccines.  Economical studies to improve production media.  Comparative studies between field strains and those that are in use for vaccine production in search for immunogenic strains.  Monthly and annual reports of the section.

b). Survey of bacterial diseases of economical importance e.g. haemorrhagic septicaemia, anthrax, blackleg, bovine farcy, John’s disease, tuberculosis and brucellosis.

c). Research: I have conducted research in different field of microbiology, improving vaccine quality and isolating a etiological agents of certain diseases for the first time in the Sudan.

Scientific achievements:-

  1. First report of infectious bovine keratoconjunctivitis and isolation of Moraxella bovis for the first time in the Sudan. Preparation of a selective diagnostic medium for isolation of Moraxella bovis. 
  2. First report of Salmonella typhimurium Copenhagen from pigeon.
  3. First report of Actinobacillus actinoides from a pneumonic lung of calves in Sudan and Africa.
  4. Drew the attention, with other colleagues, to the predisposing of dogs to canine distemper if the infection is preceded by Nocardia astertoides.
  5. Preparation of economic medium for production of blackleg vaccine: Sixteen times more.
  6. Isolation of a bacteriocin from Bacillus cereus which is inhibitory for Clostridium chauvoei and hence explained the failure of isolation of the latter for several years. Using a transport medium, I was able to make the first successful isolation of Clostridium chauvoei in the Sudan.  The bacteriocin isolated was proved to be inhibitory for chauvoei both in vitro and in vivo.
  7. First report of isolation of Actinobacillus lignieresii and its association with Pasteurella multocida in causation of pneumonia in sheep.
  8. Isolation of mycolic acid from Sudanese strains of Nocardia farcinica in enough quantities that permit the designation of Mycobacterium.
  9. Reporting both type (A) and (B) of Clostridium novyi from a case of gas gangrene in a cow and an outbreak of blackleg disease in sheep respectively. First report in the Sudan and second in Africa.
  10. Isolation of Serratia marcescens from dead honeybees larvae. First report in the Sudan.  Second in the literature regarding larvae.
  11. First report of sheep abscess syndrome.
  12. First report of goat abscess syndrome in Sudan.
  13. Isolation of legionella pneumophila from water air conditions.
  14. Black leg vaccine using Clostridium chauvei strain Kadogli.
  15. Production of vaccine for Sheep Abscess Syndrome – Morel’s Disease – Sano-Vac.
  16. Bovine – Farcy Attenuated Vaccine.
  17. Investigation on a new function of the liver i.e. attenuation of Bacteria.
  18. Detection of the sites for reception of Bacillus thuringensis toxins of larvae of Anopheles mosquito.
  19. Dental Caries vaccine. Induction of protective immunity aginst Stereptococcus mutans using cell-free and cell associated with glucose transferase.
  20. Awarded the certificate of International WHO’s who of Intellectuals for distinguished achievements. Eighth edition, July 1988.
  21. Awarded the certificate of Distinguished Leadership by the American Biographical Institute, 1989. (See qualifications).

d) Training: During my stay in the Veterinary Research Laboratory, I was able to train several veterinarians as proper bacteriologists. They obtained their higher degrees. They also had a proper training in vaccine production, surveys and scientific writing. Training of newly recruited veterinarians as well as technicians and A/technicians.  Training of veterinarians from other universities for short periods.