Publications Papers In Refreed Scientific Journals

EL-Safi, S.H., and Evans, D. (1989). A comparison of the direct Agglutination test and enzyme- linked immunosorbent assay (ELISA) in […]

  1. EL-Safi, S.H., and Evans, D. (1989). A comparison of the direct Agglutination test and enzyme- linked immunosorbent assay (ELISA) in the sero-diagnosis of leishmaniasis in the Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene. 83, 334-337. (U.K).

 

  1. EL – Safi, S.H., Neal, R.R., Murphy and Bryceson, A.A. (1990). Double – blind clinical trial with paromomycin ointment in the treatment of cutaneous leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 84,690- 691. (U.K).
  2. EL – Safi, S.H., and Peters, W., (1991) .Studies on the leishmaniases in the Sudan: 1. Epidemic of cutaneous leishmaniasis in Khartoum. Transactions of the Royal Society of Tropical Medicine and Hygiene. 85, 44-47. (U.K).

 

  1.     EL – Safi, S.H., Peters W., El-Toam, B., El-Kadarow, A. and Evans, D.A. (1991). Studies on the leishmaniases in the Sudan : 2. Clinical and parasitological studies on cutaneous leishmaniasis. Transactions of the Royal Society of tropical Medicine and Hygiene. 85, 457-464.(UK).

 

  1.     EL – Safi, S.H., Peters W. and Evans, D. (1991). Studies on the leishmaniases in the Sudan :3. Clinical and parasitological studies on visceral and mucosal leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene. 85, 465-470.(UK).

 

  1. Kadaru A.G., EL-Toam B., EL – Safi, S.H., Badi A., Humeida S., A/Galil, A. (1987). Cutaneous leishmaniasis at the Tropical Diseases Hospital in Omdurman. Sudan Medical Journal, Special Issue.12.

 

  1. Wallace G.R. ,Ball A.E, Mac Farlane J., EL – Safi, S.H. , Miles M.M and Kelly J.M. (1992) .Mapping of Visceral leishmaniasis – Specific Immunodominant B-Cell Epitope of Leishmania Donovani. Hsp 70. Infection and Immunity. 60, 2688-2693.(USA).

 

  1. Karp C.L , EL – Safi, S.H., Wynn T.A, Satti M.M, Kordofani A.M., Hag Ali, M. Neva F.A., Nutman T.B. and Sacks D.L. (1993). In Vivo Cytokine Profiles in Patients with Kala-azar: Marked Elevation of both IL- 10 and IFN. The Journal of Clinical Investigation. 91, 1644-1648.(USA).

 

  1. Hashim F.A., Ali M.S., Satti M.M, El-Hassan A.M, Ghalib H. W., EL – Safi, S.H. and El Hag I. A (1994). An outbreak of acute kala-azar in a nomadic tribe in western Sudan: features of the disease in a previously non-immune population. Transactions of the Royal Society of Tropical Medicine and Hygiene. 88, 431 – 432. (UK).
  2. EL Safi, S.H. (1995). Leishmaniasis in the Sudan. 1. Review of parasitological and serological studies on visceral leishmaniasis. Sudan Medical Journal. 33, 105-111.

 

  1. EL – Safi, S.H., Karoam A.H., Hummeida, M., Khaair, M.M, Hammad, A., Hassan, G., Harith, A., Jacquet and Le Ray, D. (1995). leishmaniasis in the Sudan II. Field evaluation of the direct agglutination Test Kit for the routine diagnosis of visceral Leishmaniasis (DAT – VL Kit) in Gedarif area, Eastern Sudan. preliminary results. Sudan Medical Journal. 33, .113-123.

 

  1. EL – Safi, S.H., Badi, M.; Neal, R.; Evans, D. and Peters, W. (1995). Leishmaniasis in the Sudan. III Isoenzymes characterization of Leishmania species responsible for cutaneous and visceral leishmaniasis. Sudan Medical Journal. 33,125-135.

 

  1. El-Harith A., Chowdhury S. AL- Masum A., Semiao Santos S, Karim, E. EL – Safi, S.H.& Haque I. (1995). Evaluation of cleaving agents other than trypsin in direct agglutination test for further improving diagnosis of visceral leishmaniasis. Journal of Clinical Microbiology, 33, 1984-1988.(USA).

 

*14.   Moody A.H. and EL – Safi, S.H. (1996). A latex agglutination test for the serodiagnosis of visceral leishmaniasis in Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene. 90,522.(UK).

 

*15.   Sugimoto C., Kitamura T., Gou J., Al-Ahdal M.N., Shchelkunov S.N., Otova B., Ondrejka .P, Chollet J. Y, EL – Safi, S.H. , etal. (1997). Typing of urinary JC virus DNA offers a novel means of tracing human migrations. Proceedings of The National Academy of Science. 94, 9191-9196. (USA).

*16.   Khalil, E.A.G., Hashim, E. A., Ghalib, H.W., Zijlstra, E. E., EL Hag., 1, A., Satti M. H. , Mustafa M. D., Kordofani, A, EL – Safi, S.H. ,S., Hag Ali, M., Siddig Ali, and EL-Hassan, A. M. (1998). Comparative study of liposomal amphotericin B (Am Bisome) and sodium stibogluconate in the treatment of Kala-azar in the Sudan. East African Medical Journal. 75, 481-484.(Kenya).

 

*17.   Boelaert M., EL – Safi, S.H., Jacquet D., De Muynck A., Stuyft P.V., and Le Ray D. (1999). Operational validation of the direct agglutination test for diagnosis of visceral leishmaniasis. American Journal of Tropical Medicine & Hygiene. 60, 129-134.(USA).

 

*18.   Boelaert M., EL – Safi, S.H., Goetghebeur E. , Gomes- Pereira S., Le Ray D. and Stuyft P.V. (1999). Latent class analysis permits unbiased estimates of the validity of DAT for the diagnosis of visceral leishmaniasis. Tropical Medicine and International Health. 4, 395-401.(Belgium).

 

*19.   Boelaert M., EL – Safi, S.H. , Mousa H., Githure J., Mbati P., Gurubacharya V.L, J. Shrestha, Jacquet D., De Muynck A., Le Ray, D.and Stuyft P.V. ( 1999). Multi-centre evaluation of repeatability and reproducibility of the direct agglutination test for visceral leishmaniasis.Tropical Medicine and International Health. 4, 31-37.(Belgium).

*20.   Dereure J., Boni M., Pratlong, El- Hadi M., Bucheton B. , EL – Safi, S.H., Feugier E. , Khair M.M., Davoust B., Dessein A.and Dedet J.P. (2000). Visceral leishmaniasis in Sudan: first identifications of Leishmania from dogs. Transactions of the Royal Society of Tropical Medicine and Hygiene. 94, 154-155.(UK).

*21.   Mukhtar M.M., Sharief A.H., EL – Safi, S.H., Harith A.E., Higazzi T.B., Aadm A.M.and Abdalla H.S. (2000). Detection of antibodies to Leishmania donovani in animals in a kala-azar endemic region in eastern Sudan: a preliminary report. Transactions of the Royal Society of Tropical Medicine and Hygiene. 94, 33 – 36.(UK).

*22.   Attar Z.J., Chance M.L., EL – Safi, S.H., Dourado C., Carney J., Azazy A. , El-Hadi M.and Hommel M. (2001). Latex agglutination test for the detection of urinary antigens in visceral leishmanaisis . Acta Tropica. 78, 11-16.(Netherlands).

 

*23.   El-Tai, N.O. El Fari M., Mauricio I., Miles M.A., Oskam L., EL – Safi, S.H., Presber W.H., and Schonian G.(2001). Leishmania donovani: Intraspecific polymorphisms of Sudanese isolates revealed by PCR-based analyses and DNA Sequencing. Experimental Parasitology. 97, 35-44. (U.S.A).

 

*24. Pratlong, F., Dereure J., Bucheton B., EL – Safi, S.H. , Dessein A, L anotte G. and Dedet J.P. (2001). Sudan: The possible original focus of visceral leishmaniasis, Parasitology. 122, 599- 605.(U.S.A).

 

*25.   Alvar J., Antunes F., Berhe B., Cacopardo B., Dedet J.P, Deniau M., Desjeux P., Henri Dumon, EL – Safi, S.H. , Gradoni L. et. al. (2001). Conclusions and Recommendations of the IVTH Joint Meeting on Leishmania /HIV co-infections, Parasite 8. 376-379(France).

*26.   Lambert M., Dereure J., EL – Safi, S.H., Bucheton B., Dessein A., Boni M., Feugier E. and Dedet J.P. (2002). The sandfly fauna in the visceral –leishmaniasis focus of Gedaref, in the Atbara-River area of eastern Sudan. Annals of Tropical Medicine & Parasitology. 96, 631-636 .(UK).

 

*27.   EL – Safi, S.H., Bucheton B., Kheir M.M, Musa H.A., EL-Obaid M. , Hammad A.and Dessein A. (2002). Original Article: Epidemiology of visceral leishmaniasis in Atbara River area, eastern Sudan: the outbreak of Barbar El Fugara village (1996 –1997). Microbes and Infection . 4, 1439-1447 .(France).

 

*28.   Bucheton, B., Kheir M.M, EL – Safi, S.H. , Hammad A., Mergani A., Mary C., Abel L., and Dessein A.. (2002). The interplay between environmental and host factors during an outbreak of visceral leishmaniasis in Eastern Sudan. Microbes and Infection. 4, 1449-1457.(France).

 

EL – Safi, S.H. (2003). Visceral leishmaniasis Diagnosis: Operational Research in Tropical Diseases. Final Report Summaries 1992-2000. Regional Office for the Eastern Mediterranean, Word Health Organization, 17-19.

 

*30.   Bucheton, B., Abel L., Kheir M.M, Mirghani A., EL – Safi, S.H., Chevillard C., and Dessein A. (2003). Genetic control of visceral leishmaniasis in a Sudanese population: Candidate gene testing indicates a linkage to the NRAMP1 region. Genes & Immunity .4, 104-109.(U.K).

*31.   Dereure J, EL – Safi, S.H., Bucheton B, Boni M, Kheir MM, Davoust B, Pratlong F,Feugier E, Lambert M, Dessein A, Dedet JP. (2003) . Visceral leishmaniasis in eastern Sudan: parasite identification in humans and dogs; host-parasite relationships. Microbes and Infection. 5,1103-1108.(France).

*32.   Bucheton B, Abel L, EL – Safi, S.H., Kheir MM, Pavek S, Lemainque A, Dessein A. (2003). A major susceptibility locus on chromosome 22q12 plays a critical role in the control of kala-azar. American Journal of Human Genetics. 73,1052-1060.(USA).

*33.   Bucheton, §B.,§EL – Safi, S.H. , Hammad A., Kheir M.M., Eudes N., Mergani A., Dessein A., and Mary C. (2003). Anti-Leishmania antibodies in an outbreak of visceral leishmaniasis in Eastern Sudan: High antibody responses occur in resistant subjects and are not predictive of disease. Transactions of the Royal Society of Tropical Medicine & Hygiene. 97, 463-468.(UK).

 

*34.   EL – Safi, S.H., Abdelhaleem A. , Hammad A. , El-Basha I., Omer A. Gad Kareem H., Boelaert M. , Chance M., Hommel M. (2003). Field evaluation of the latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan. Eastern Mediterranean Health Journal.9 (4):844-55.

*35.   Dessein, A., Bucheton B., Argiro, L., Elwali, N., Rodrigues V., Chevillard C., Marquet, S., EL – Safi, S.H.and Abel L. (2004). Human susceptibility to visceral leishmaniasis (Leishmania donovani) and to schistosomiasis (shistosoma mansoni) is contllored by major genetic loci. Infectious Disease and Host-Pathogen Evolution. Editd by Krishna R. Dronamraju. Cambridge University Press. 241-261.(UK).

 

*36.   EL – Safi, S.H., Hamid N. , Omer A. , Abdel/Haleem A. , Hammad A.,   Gad Kareem H. and Boelaert M.(2004). Infection rates with Leishmania and M.tuberculosis in a village endemic for visceral leishmaniasis in eastern Sudan. Tropical Medicine and International Health. 9, (12):1305-11.l( Belgium).

*37. Mohammed IM., Karrar, Z. & EL – Safi, S.H.(2006). Coeliac disease in Sudanese   children with clinical features suggestive of the disease. Eastern Mediterranean       Health Journal .12(5):582-9. (WHO/Egypt). *38. El-Safi S H, Kheir MM, Bucheton B, Argiro L, Abel L, Dereure J, Dedet JP,Dessein A.(2006) Genes and environment in susceptibility to visceral leishmaniasis.C R Biol.329(11):863-70.  *39. Bucheton B, Argiro L, Chevillard C, Marquet S, Kheir MM, Mergani A, El-Safi SH, Dessein AJ.(2007). Identification of a novel G245R polymorphism in the IL-2 receptor beta membrane proximal domain associated with human visceral leishmaniasis.Genes & Immunity. 8(1):79-83.*40. Boelaert M, El-Safi SH, Hailu A, Mukhtar M, Rijal S, Sundar S, Wasunna M,Aseffa A, Mbui J, Menten J, Desjeux P, Peeling RW.(2008).         Diagnostic tests for kala-azar: a multi-centre study of the freeze-dried DAT,rK39 strip test and KAtex in East Africa and the Indian subcontinent.Transactions of The Royal Society of Tropical Medicine & Hygiene.102(1):32-40.

*41. Boelaert*M. , Bhattacharya S., Chappuis F., .El Safi S H, .Hailu A.,.Mondal D., Rijal S., Sundar S., Peeling R. (2007).

 

How to evaluate rapid diagnostic tests for Visceral Leishmaniasis .Nature Microbiology Reviews.S7- S16.

*42 . Deborggraeve S, Laurent T, Espinosa D, Van der Auwera G, Mbuchi M, Wasunna  M, El-Safi S, Al-Basheer AA, Arévalo J, Miranda-Verástegui C, Leclipteux T,  Mertens P, Dujardin JC, Herdewijn P, Büscher P. A simplified and standardized  polymerase chain reaction format for the diagnosis of leishmaniasis.Journal of Infectious Diseases.( 2008) 15;198(10):1565-72.

43. Maira G R Pitta, Audrey Romano, Sandrine Cabantous, Sandrine Henri, Awad      Hammad, Laurent Argiro, Musa el Kheir, Bruno Bucheton, Charles Mary,Sayda Hassan El-Safi & Alain Dessein. IL-17 and IL-22 in protection against human Kala Azar caused by Leishmania Donovan ( acceped).v