{"id":21,"date":"2017-11-15T13:13:36","date_gmt":"2017-11-15T13:13:36","guid":{"rendered":"http:\/\/staffpages.uofk.edu\/humeida\/?page_id=21"},"modified":"2023-01-28T14:45:01","modified_gmt":"2023-01-28T14:45:01","slug":"publications","status":"publish","type":"page","link":"https:\/\/staffpages.uofk.edu\/humeida\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Publications<\/span>
\n1. P.L. Birch, H.A. El-Obeid and M. Akhtar, “The Preparation of Chloromethylketone Analogues of Amino Acids: Inhibition of Leucine Aminopeptidase”. Archives of Biochemistry and Biophysics, 148,<\/span>
\n447-451 (1972).<\/span>
\n2. M. Akhtar and H.A. El-Obeid, “Inactivation of Serine Transhydroxymethylase and Threonine Aldolase Activities”. Biochim. Biophys. Acta, 258, 791-799(1972).<\/span>
\n3. H.A. El-Obeid and M. Akhtar, “Glycidaldehyde: An Inhibitor Directed Towards the C1-Unit Binding Site of Serine Transhydroxymethylase”. Biochem. Soc. Trans., 128 (1973).<\/span>
\n4. Muhammad Akhtar, Humeida Ali El-Obeid and Peter M. Jordan, Mechanistic, Inhibitory and Stereochemical Studies on Cytoplasmic and Mitochondrial Serine Transhydroxymethylases”. Biochem. J., 145,<\/span>
\n159-168 (1975).<\/span>
\n5. Peter M. Jordan, Humeida A. El-Obeid, David L. Corina and Muhammad Akhtar. “Mechanism of C2-C3 Bond Formation and Cleavage in Serine Transhydroxymethylase Reactions”. J.C.S. Chem. Comm (2)., 73-74 (1976).<\/span>
\n6. Hassan Y. Aboul-Enein, Humeida A. El-Obeid and A.A. El-Farra. “Synthesis and Monoamine Oxidase Inhibitory Activity of Some Pentafluorobenzylidines and their Corresponding Hydrazines.” Pharm. Acta. Helv., 10, 282-284 (1980).<\/span>
\n7. H.A. El-Obeid, A.E. Madani and D.R. Feller, “Spectral and Enzymatic Characteristics of the N-Demethylation of Ep -Phenyl Homolog in Rabbit Liver Microsomes”, The Pharmacologist, 25, 856 (1983).<\/span><\/p>\n

8.T.A. Kocarek, H.A. El-Obeid, A.E. Madani and D.R. Feller,<\/span>
\n“N- -Phenyl Homolog in<\/span>
\nRabbit Liver Microsomes: Effect of Induction”, The Pharmacologist, 26, 242 (1984).<\/span>
\n9. Humeida A. El-Obeid, Elamin I. Elnima and Abdullah A. Al-Badr, “Synthesis and Antimicrobial Activity of New Furan Derivatives”, Pharm. Res., 55, 42-3 (1985).<\/span>
\n10. Humeida A. El-Obeid, A.E. Madani, K.A. Al-Rashood, K.E.H. El-Tahir,<\/span>
\nA. Tilmisani and M.E. Ibrahim, “Synthesis and Pharmacological Activity of N- Alkyl-1,2-Diphenylethanolamines”, Pharmaceutical Research, 4, 166-170 (1987).<\/span>
\n11. K.E.H. El Tahir, H.A. El-Obeid, K.A. Al-Rashood, A.E. Madani and A.M. Ageel, \u201cThe Antiarrhythmic Activity of N-Alkyl-1,2-<\/span><\/p>\n

Diphenylethanolamunes\u201dPharm. Res., 6, 252-4 (1988)<\/span>
\n12. K.A. Al-Rashood, A.A. Mustafa, A.A. Alhaider, O.T. Ginawi, A.E. Madani and H.A. El-Obeid, \u201cAntipsychotic Properties of New N-(4-Substituted- 1-Piperazinylethyl)- and N-(4-Substituted-1- piperidinylethyl) Phthalimides\u201d, J. Pharm. Sci., 77, 898-901 (1988).<\/span>
\n13. K.A. Al-Rashood, A.E. Madani, O.T. Ginawi, S.A. Ashraf and H.A.<\/span>
\nEl-Obeid, “Synthesis and Antinociceptive Activity of Ring Substituted N-[2- Phenyl-2-hydroxy)ethyl]-4-phenyl-4-carboethoxy-piperidines”, Arzneim.-Forsch.\/Drug Research, 40, 1242-1245 (1990).<\/span>
\n14. K.E.H. El Tahir, M.A.S. El-Naser, A.M. Ageel, H.E. El-Obeid and K.A. Al-Rashood, “Antiaggregatory Activity of N-Methyl- and<\/span>
\nN-Isobutyl-1,2-Diphenyl Ethanolamines in Rat Platelets”, Archives internationales de Pharmacodynamie et de Therapie, 307, 162-171 (1990).<\/span>
\n15. K.E.H. El-Tahir, M.A.S. El-Naser, A.M. Ageel, H.A. El-Obeid and K.A. Al-Rashood, “Cardiovascular Depressant Effects of N-Methyl- and<\/span>
\nN-Isobutyl-1,2-Diphenyl Ethanolamines: Elucidation of the Mechanisms of Action”, Archives internationales de Pharmacodynamie et de Therapie, 309, 88-102 (1991).<\/span>
\n16. K.E.H. El-Tahir, M.A.E. El-Naser, A.M. Ageel, H.A. El-Obeid, “Effects of N-Methyl- and N-Isobutyl-1,2-Diphenyl Ethanolamine on the Spontaneous and Evoked Contractions in the Rat Isolated Uterus”, Gen. Pharmac., 22, 685-690 (1991).<\/span>
\n17. A.A. Mustafa, H.A. El-Obeid and K.A. Al-Rashood, “Long Lasting Inhibition of Food Intake in the Rat by a New Phthalimidoethylpiperazine Derivative”, Research Comm. In Chem. Path. and Pharmacol.,18,25-36 1993.<\/span>
\n18. H.A. El-Obeid, K.A. Al-Rashood, H.A. Al-Khamees, K.I. Al-Khamis and<\/span>
\nM.S. Mian, “Effect of Pirenzepine on the N-Demethylation of D(-<\/span>
\n)Ephedrine and Ethylmorphine by Rat Liver Microsomes”, Biopharm. & Drug Dispos., 14, 271-277 (1993).<\/span>
\n19. K.A. Al-Rashood, H.A. Al-Khamees, K.I. Al-Khamis, M.S. Mian and H.A. El-Obeid -Hydroxyclobazam Metabolism by Desmethylclobazam and Carbamazepine-10,11-epoxide Using Rabbit Liver Microsomes”, J. Pharm. Med., 4, (1994).<\/span>
\n20. H.A. Al-Khamees, K.A. Al-Khamis, K.A. Al-Rashood, M.S. Mian and H.A. El-Obeid, “Studies on the Kinetics of the in vitro N-demethylation of Tenoxicam and Pirenzepine and their Interaction with Clobazam Metabolism in Rabbit Liver Microsomes”, J. Pharm. Med., 4, 53-59 (1994).<\/span>
\n21. Faiza S. El-Shafie, Omar A. Al-Deeb, Mona E.M. Hammad, Ali A. Mustafa and Humeida A. El-Obeid, \u201cSynthesis and Analgesic Activity of New<\/span>
\n1-(p-Substituted Phenyl)-4-Substituted Piperazines and Piperidines and their Carbinol Derivatives\u201d, Sci. Pharm., 62, 389-403 (1994)<\/span>
\n22. Omar A. Al-Deeb, Faiza S. El-Shafie, Mona E. Hammad, Ali A. Mustafa and Humeida A. El-Obeid, \u201c13C and 1H Nuclear Magnetic Resonance Spectral Studies on Some 1,4-Disubstituted Piperazine Derivatives\u201d, Saudi Pharmaceutical Journal, 5, 103-109 (1997).<\/span>
\n23. Dana M. Bakheet, K.E.H. El-Tahir, M.I. Al-Sayed, H.A. El-Obeid and<\/span>
\nK.A. Al-Rashood, \u201cStudies on the Cardiovascular Depressant Effects of N-ethyl- and N-benzyl-1,2-diphenylethanolamines in Rat: Elucidation of<\/span><\/p>\n

Mechanisms of Action\u201d, General Pharmacology, the Vascular System, 33, 17-22 (1999).<\/span>
\n24. D.M. Bakhett, K.E.H. El Tahir, M.I. Al-Sayed, H.A. El-Obeid and K.A. Al-Rashood, \u201cStudies on the Spasmolytic and Uterine Relaxant Actions of N-ethyl- and N-benzyl-1,2-Diphenylethanolamines: Elucidation of the Mechanisms of Action\u201d. Pharmacological Research, 39, 463-470 (1999).<\/span>
\n25. Sami G. Abdelhamid, Humeida A. El-Obeid, Abdelrahman A Al-Majed, Hassan A. El-Kashef and Hussein I. El-Sabbagh, \u201cSynthesis and Anticonvulsant Activity of Some New 4-Oxo-3H-quinazoline Analogs\u201d. Med Chem Res,10,378-389(2001).<\/span>
\n26. S. G. Abdelhamid, H. A. El-Obeid, K. A. Al-Rashood, A. A. Khalil and H. El- Sabbagh, \u201dSubstituted Quinazolines: 1. Synthesis and Antitumor Activity of Certain Substituted 2-Mercapto-4(3H)-quinazoline Analogs.\u201dScientiaPharmaceutia (Sci. Pharm.), 69,351-A366(2001).<\/span>
\n27. E.A. Gadkariem, H.A. El-Obeid, M.A. Abounassif, S.M. Ahmed, K.E.E. Ibrahim, \u201cEffects of Alkali and Simulated gastric and Intestinal Fluids on Danazol Stability\u201d. J.Phamaceut. Biomed. Anal, 31,743-751(2003).<\/span>
\n28. E.A. Gadkariem, H.A. El-Obeid, F. Belal, M.A. Abounassif, K.E.E. Ibrahim, \u201cChemical and Photochemical Stability Studies on Diloxanide Furoate in Carbohydrates and Polyols Solutions\u201d. J. Food and Drug Analysis, 12, 299-305(2003).<\/span>
\n29. E.A. Gadkareim, F. Belal, M.A. Abounassif, H.A. El-Obeid, K.E.E. Ibrahim, \u201cStability Studies on Diloxanide Furoate: Effect of pH, Temperature, Gastric and Intestinal Fluids\u201d. Il Farmaco, 59, 323- 329(2004).<\/span>
\n30. M.A. Abounassif, H.A. El-Obeid, E.A. Gadkariem, \u201cStability Studies on Some Benzocycloheptane Antihistaminic Agents. J. Pharmaceut. Biomed. Anal. 36, 1011-1018(2005).<\/span>
\n31. Ali Aboel Dahab, Dhia Eldin A. Elhag, Ammar Bourai Ahmed and Humeida A. El-Obeid. \u201cDetermination of elemental toxicity migration limits, bioaccessibility and risk assessment of essential childcare products\u201d.<\/span>
\nEnviron. Sci. Pollut. Res., DOI 10.1007\/s11356-015-5594-0 (2015).<\/span><\/p>\n

[The results of some of these published researches had been cited in International Medicinal Chemistry and Biochemistry Textbooks and reference books].<\/span><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Publications 1. P.L. Birch, H.A. El-Obeid and M. Akhtar, “The Preparation of Chloromethylketone Analogues of Amino Acids: Inhibition of Leucine […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"page-publications.php","meta":{"footnotes":""},"class_list":["post-21","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/pages\/21","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/comments?post=21"}],"version-history":[{"count":5,"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/pages\/21\/revisions"}],"predecessor-version":[{"id":53,"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/pages\/21\/revisions\/53"}],"wp:attachment":[{"href":"https:\/\/staffpages.uofk.edu\/humeida\/wp-json\/wp\/v2\/media?parent=21"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}