Professor

Professor

  • Personal Information
  • Qualification Information
  • Academic Information
  • Publications
  • REVIEW ARTICLES
  • ANALYTICAL RESEARCH ARTICLES
  • ABSTRACTS PRESENTED BEFORE MEETINGS (HUMEIDA ALI EL-OBEID, Ph.D.)
  • Other

Publications

Publications
1. P.L. Birch, H.A. El-Obeid and M. Akhtar, “The Preparation of Chloromethylketone Analogues of Amino Acids: Inhibition of Leucine Aminopeptidase”. Archives of Biochemistry and Biophysics, 148,
447-451 (1972).
2. M. Akhtar and H.A. El-Obeid, “Inactivation of Serine Transhydroxymethylase and Threonine Aldolase Activities”. Biochim. Biophys. Acta, 258, 791-799(1972).
3. H.A. El-Obeid and M. Akhtar, “Glycidaldehyde: An Inhibitor Directed Towards the C1-Unit Binding Site of Serine Transhydroxymethylase”. Biochem. Soc. Trans., 128 (1973).
4. Muhammad Akhtar, Humeida Ali El-Obeid and Peter M. Jordan, Mechanistic, Inhibitory and Stereochemical Studies on Cytoplasmic and Mitochondrial Serine Transhydroxymethylases”. Biochem. J., 145,
159-168 (1975).
5. Peter M. Jordan, Humeida A. El-Obeid, David L. Corina and Muhammad Akhtar. “Mechanism of C2-C3 Bond Formation and Cleavage in Serine Transhydroxymethylase Reactions”. J.C.S. Chem. Comm (2)., 73-74 (1976).
6. Hassan Y. Aboul-Enein, Humeida A. El-Obeid and A.A. El-Farra. “Synthesis and Monoamine Oxidase Inhibitory Activity of Some Pentafluorobenzylidines and their Corresponding Hydrazines.” Pharm. Acta. Helv., 10, 282-284 (1980).
7. H.A. El-Obeid, A.E. Madani and D.R. Feller, “Spectral and Enzymatic Characteristics of the N-Demethylation of Ep -Phenyl Homolog in Rabbit Liver Microsomes”, The Pharmacologist, 25, 856 (1983).

8.T.A. Kocarek, H.A. El-Obeid, A.E. Madani and D.R. Feller,
“N- -Phenyl Homolog in
Rabbit Liver Microsomes: Effect of Induction”, The Pharmacologist, 26, 242 (1984).
9. Humeida A. El-Obeid, Elamin I. Elnima and Abdullah A. Al-Badr, “Synthesis and Antimicrobial Activity of New Furan Derivatives”, Pharm. Res., 55, 42-3 (1985).
10. Humeida A. El-Obeid, A.E. Madani, K.A. Al-Rashood, K.E.H. El-Tahir,
A. Tilmisani and M.E. Ibrahim, “Synthesis and Pharmacological Activity of N- Alkyl-1,2-Diphenylethanolamines”, Pharmaceutical Research, 4, 166-170 (1987).
11. K.E.H. El Tahir, H.A. El-Obeid, K.A. Al-Rashood, A.E. Madani and A.M. Ageel, “The Antiarrhythmic Activity of N-Alkyl-1,2-

Diphenylethanolamunes”Pharm. Res., 6, 252-4 (1988)
12. K.A. Al-Rashood, A.A. Mustafa, A.A. Alhaider, O.T. Ginawi, A.E. Madani and H.A. El-Obeid, “Antipsychotic Properties of New N-(4-Substituted- 1-Piperazinylethyl)- and N-(4-Substituted-1- piperidinylethyl) Phthalimides”, J. Pharm. Sci., 77, 898-901 (1988).
13. K.A. Al-Rashood, A.E. Madani, O.T. Ginawi, S.A. Ashraf and H.A.
El-Obeid, “Synthesis and Antinociceptive Activity of Ring Substituted N-[2- Phenyl-2-hydroxy)ethyl]-4-phenyl-4-carboethoxy-piperidines”, Arzneim.-Forsch./Drug Research, 40, 1242-1245 (1990).
14. K.E.H. El Tahir, M.A.S. El-Naser, A.M. Ageel, H.E. El-Obeid and K.A. Al-Rashood, “Antiaggregatory Activity of N-Methyl- and
N-Isobutyl-1,2-Diphenyl Ethanolamines in Rat Platelets”, Archives internationales de Pharmacodynamie et de Therapie, 307, 162-171 (1990).
15. K.E.H. El-Tahir, M.A.S. El-Naser, A.M. Ageel, H.A. El-Obeid and K.A. Al-Rashood, “Cardiovascular Depressant Effects of N-Methyl- and
N-Isobutyl-1,2-Diphenyl Ethanolamines: Elucidation of the Mechanisms of Action”, Archives internationales de Pharmacodynamie et de Therapie, 309, 88-102 (1991).
16. K.E.H. El-Tahir, M.A.E. El-Naser, A.M. Ageel, H.A. El-Obeid, “Effects of N-Methyl- and N-Isobutyl-1,2-Diphenyl Ethanolamine on the Spontaneous and Evoked Contractions in the Rat Isolated Uterus”, Gen. Pharmac., 22, 685-690 (1991).
17. A.A. Mustafa, H.A. El-Obeid and K.A. Al-Rashood, “Long Lasting Inhibition of Food Intake in the Rat by a New Phthalimidoethylpiperazine Derivative”, Research Comm. In Chem. Path. and Pharmacol.,18,25-36 1993.
18. H.A. El-Obeid, K.A. Al-Rashood, H.A. Al-Khamees, K.I. Al-Khamis and
M.S. Mian, “Effect of Pirenzepine on the N-Demethylation of D(-
)Ephedrine and Ethylmorphine by Rat Liver Microsomes”, Biopharm. & Drug Dispos., 14, 271-277 (1993).
19. K.A. Al-Rashood, H.A. Al-Khamees, K.I. Al-Khamis, M.S. Mian and H.A. El-Obeid -Hydroxyclobazam Metabolism by Desmethylclobazam and Carbamazepine-10,11-epoxide Using Rabbit Liver Microsomes”, J. Pharm. Med., 4, (1994).
20. H.A. Al-Khamees, K.A. Al-Khamis, K.A. Al-Rashood, M.S. Mian and H.A. El-Obeid, “Studies on the Kinetics of the in vitro N-demethylation of Tenoxicam and Pirenzepine and their Interaction with Clobazam Metabolism in Rabbit Liver Microsomes”, J. Pharm. Med., 4, 53-59 (1994).
21. Faiza S. El-Shafie, Omar A. Al-Deeb, Mona E.M. Hammad, Ali A. Mustafa and Humeida A. El-Obeid, “Synthesis and Analgesic Activity of New
1-(p-Substituted Phenyl)-4-Substituted Piperazines and Piperidines and their Carbinol Derivatives”, Sci. Pharm., 62, 389-403 (1994)
22. Omar A. Al-Deeb, Faiza S. El-Shafie, Mona E. Hammad, Ali A. Mustafa and Humeida A. El-Obeid, “13C and 1H Nuclear Magnetic Resonance Spectral Studies on Some 1,4-Disubstituted Piperazine Derivatives”, Saudi Pharmaceutical Journal, 5, 103-109 (1997).
23. Dana M. Bakheet, K.E.H. El-Tahir, M.I. Al-Sayed, H.A. El-Obeid and
K.A. Al-Rashood, “Studies on the Cardiovascular Depressant Effects of N-ethyl- and N-benzyl-1,2-diphenylethanolamines in Rat: Elucidation of

Mechanisms of Action”, General Pharmacology, the Vascular System, 33, 17-22 (1999).
24. D.M. Bakhett, K.E.H. El Tahir, M.I. Al-Sayed, H.A. El-Obeid and K.A. Al-Rashood, “Studies on the Spasmolytic and Uterine Relaxant Actions of N-ethyl- and N-benzyl-1,2-Diphenylethanolamines: Elucidation of the Mechanisms of Action”. Pharmacological Research, 39, 463-470 (1999).
25. Sami G. Abdelhamid, Humeida A. El-Obeid, Abdelrahman A Al-Majed, Hassan A. El-Kashef and Hussein I. El-Sabbagh, “Synthesis and Anticonvulsant Activity of Some New 4-Oxo-3H-quinazoline Analogs”. Med Chem Res,10,378-389(2001).
26. S. G. Abdelhamid, H. A. El-Obeid, K. A. Al-Rashood, A. A. Khalil and H. El- Sabbagh, ”Substituted Quinazolines: 1. Synthesis and Antitumor Activity of Certain Substituted 2-Mercapto-4(3H)-quinazoline Analogs.”ScientiaPharmaceutia (Sci. Pharm.), 69,351-A366(2001).
27. E.A. Gadkariem, H.A. El-Obeid, M.A. Abounassif, S.M. Ahmed, K.E.E. Ibrahim, “Effects of Alkali and Simulated gastric and Intestinal Fluids on Danazol Stability”. J.Phamaceut. Biomed. Anal, 31,743-751(2003).
28. E.A. Gadkariem, H.A. El-Obeid, F. Belal, M.A. Abounassif, K.E.E. Ibrahim, “Chemical and Photochemical Stability Studies on Diloxanide Furoate in Carbohydrates and Polyols Solutions”. J. Food and Drug Analysis, 12, 299-305(2003).
29. E.A. Gadkareim, F. Belal, M.A. Abounassif, H.A. El-Obeid, K.E.E. Ibrahim, “Stability Studies on Diloxanide Furoate: Effect of pH, Temperature, Gastric and Intestinal Fluids”. Il Farmaco, 59, 323- 329(2004).
30. M.A. Abounassif, H.A. El-Obeid, E.A. Gadkariem, “Stability Studies on Some Benzocycloheptane Antihistaminic Agents. J. Pharmaceut. Biomed. Anal. 36, 1011-1018(2005).
31. Ali Aboel Dahab, Dhia Eldin A. Elhag, Ammar Bourai Ahmed and Humeida A. El-Obeid. “Determination of elemental toxicity migration limits, bioaccessibility and risk assessment of essential childcare products”.
Environ. Sci. Pollut. Res., DOI 10.1007/s11356-015-5594-0 (2015).

[The results of some of these published researches had been cited in International Medicinal Chemistry and Biochemistry Textbooks and reference books].